Entries in Vaginal Rejuvenation (2)


New fertility treatment

There is no human life without beneficial bacteria. There is no conception, implantation and fetal growth without the right set of beneficial vaginal, cervical, placental bacteria.

Fertility and pregnancy success may be greatly enhanced by vaginal microbiome transplantation from healthy young pregnant women.



Hum Reprod. 2016 Apr;31(4):795-803. doi: 10.1093/humrep/dew026. Epub 2016 Feb 23.

Abnormal vaginal microbiota may be associated

with poor reproductive outcomes:

a prospective study in IVF patients.



What is the diagnostic performance of qPCR assays compared with Nugent scoring for abnormal vaginal microbiota and for predicting the success rate of IVF treatment?


The vaginal microbiota of IVF patients can be characterized with qPCR tests which may be promising tools for diagnosing abnormal vaginal microbiota and for prediction of clinical pregnancy in IVF treatment.


Bacterial vaginosis (BV) is a common genital disorder with a prevalence of approximately 19% in the infertile population. BV is often sub-clinical with a change of the vaginal microbiota from being Lactobacillus spp. dominated to a more heterogeneous environment with anaerobic bacteria, such as Gardnerella vaginalis and Atopobium vaginae. Few studies have been conducted in infertile women, and some have suggested a negative impact on fecundity in the presence of BV.


A cohort of 130 infertile patients, 90% Caucasians, attending two Danish fertility clinics for in vitro fertilization (IVF) treatment from April 2014-December 2014 were prospectively enrolled in the trial.


Vaginal swabs from IVF patients were obtained from the posterior fornix. Gram stained slides were assessed according to Nugent's criteria. PCR primers were specific for four common Lactobacillus spp., G. vaginalis and A. vaginae. Threshold levels were established using ROC curve analysis.


The prevalence of BV defined by Nugent score was 21% (27/130), whereas the prevalence of an abnormal vaginal microbiota was 28% (36/130) defined by qPCR with high concentrations of Gardnerella vaginalis and/or Atopobium vaginae. The qPCR diagnostic approach had a sensitivity and specificity of respectively 93% and 93% for Nugent-defined BV. Furthermore, qPCR enabled the stratification of Nugent intermediate flora. Eighty-four patients completed IVF treatment. The overall clinical pregnancy rate was 35% (29/84). Interestingly, only 9% (2/22) with qPCR defined abnormal vaginal microbiota obtained a clinical pregnancy (P = 0.004).


Although a total of 130 IVF patients were included in the study, a larger sample size is needed to draw firm conclusions regarding the possible adverse effect of an abnormal vaginal microbiota in relation to the clinical pregnancy rate and other reproductive outcomes.


Abnormal vaginal microbiota may negatively affect the clinical pregnancy rate in IVF patients. If a negative correlation between abnormal vaginal microbiota and the clinical pregnancy rate is corroborated, patients could be screened and subsequently treated for abnormal vaginal microbiota prior to fertility treatment.


This study was funded by The AP Møller Maersk Foundation for the advancement of Medical Science and Hospital of Central Jutland Research Fund, Denmark. No competing interests.


The project was registered at clinicaltrials.gov (file number NCT02042352).





Novel Program 2016


PD Dr. med. Rainer Arendt
FMH Cardiology, Internal Medicine
Regenerative Medicine 

Klausstrasse 10
T +41 43 336 7260
M +41 78 825 0803
F +41 43 336 7261



The Dolder Grand Health & Aesthetic Link 

















  • Already today it is possible to increase the telomere length of the chromosomes, translating into an extension of human lifespan by approximately 10 years, by prudent eating, regular exercise, stress relief, regular chelation/detox treatment and especially by epigenetic rejuvenation, i.e. the gut, skin and vaginal microbiome exchange (the Élie Metchnikoff cure), with additional benefits for wellbeing, performance, fertility, increased vitality, and prevention of disease / neurodegeneration / hormonal involution (degeneration) later in life.
  • Recent scientific successes in rejuvenation, extending the lifespan, and discovery of a variety of species (including humans of advanced ages) having negligible senescence (decay due to old age), allow us to cancel accelerated or premature ageing for younger humans, reverse ageing or at least significantly delay it for older humans.
  • Our aim is to extend the lifespan in good health and full vitality




  • Epigenetics is the study, in the field of genetics, of cellular and physiological phenotypic trait variations, caused by external or environmental factors, mainly by the biofilms on our skin, in our mouth, in our lungs, in our gut, in our vagina, placenta and sexual organs,  that switch genes on and off and affect how cells read genes
  • The microbiota or microbiome is the community of commensal, symbiotic microbes that share our body space, or in a stricter sense stick to external or internal body surfaces as a biofilm
  • The microbiome and the human host emerged as a unity along evolution by a process of integration
  • The human microbiome has a significant impact on human development (before birth via the biofilm on the placenta), health and well-being
  • It is the rich array of beneficial microbes in our intestines and in our biofilms that makes us the human beings we are, preserves our health, and determines our lifespan.





  • The importance of the commensal microbiota that colonizes the skin, gut, vaginal, placental, and mucosal surfaces of the human body is being increasingly recognized through a rapidly expanding body of science studying the human microbiome
  • The human body consists of more than 90% of microbial cells. The gastrointestinal tract harbors trillions of beneficial microorganisms that influence the development and homeostasis of the host. Alterations in composition and function of the microbiota have been implicated in a multitude of metabolic and inflammatory diseases in humans
  • There is a burgeoning scientific field on the role of the human microbiome in ageing, age-related diseases, diabetes, obesity, atherosclerotic diseases,  allergic diseases, autoimmune diseases, neuropsychiatric illnesses, infections, inflammatory bowel disease, and cancer


Mayo Clin Proc. 2014;89(1):107-114

Current Opinion in Immunology 2014, 30:54–62

Best Practice & Research Clinical Gastroenterology 27 (2013) 127–137




  • The chromosomes contain almost all of a cell’s genes. The tips of every chromosome are called the telomeres, they protect the chromosome from damage
  • Each time a cell divides, a little bit of the telomere is lost (therefore, the telomeres are regarded as our biological clock). When the telomeres become very short, the cell can no longer divide and dies
  • Genetic and epigenetic factors, the interaction of the immune and hormonal systems with our microbiota, influence how quickly the telomeres shorten
  • Restauration of the youthful diversity of the human  microbiota, healthy eating styles, increased fitness, stress relief result in longer telomeres reflecting/causing extensions of our lifespan
  • We measure the length of the telomeres in a blood sample as a parameter of lifespan before and after treatment





Switzerland –the prime destination for health, vitality, rejuvenation and long life 

Since the early 18th century, Switzerland - along with Italy – began to be perceived by the contemporaries as the most beautiful landscapes in Europe. Ever since, it has been regarded a fountain of health, long before the first patients with tuberculosis were sent for the famous sun, air and mountain cures in the early 20th century.  


And especially today, Switzerland is a  frontrunner in medical technology, with a healthcare system rightfully acknowledged to be one of the best in the world, with its exceptional quality of care and the excellence of its medical facilities.

















University Hospital, main buildings of the University and the ETH, and the city of Zurich, Switzerland 




  • Ruling out treatable disease (by a comprehensive checkup examination, imaging, endoscopy, laboratory medicine)
  • Treating treatable disease, alleviating non-treatable disease (based on academic medicine and amended by the newest treatments from cellular, biological medicine, nutrition sciences, sports physiology, lifestyle medicine and neurosciences)
  • Extending the lifespan by restauration of the youthful diversity of our biofilms nIncreasing one’s resources and living well: staying quick-witted, social and sexual
  • Sidestepping risk factors for disease (preventive medicine, cardio-vascular prevention, lifestyle changes, exchanging non-beneficial microbes, neuroprotection)
  • Improving neurofunction, cardiac function by restauration of the gut-brain axis, of the gut-heart axis
  • Restauration of the senescent immune system, prevention of cancer
  • Regeneration of our endocrine (hormonal) systems




  • Prevention or treatment of accelerated arteriosclerosis of carotid or coronary arteries (stroke, heart attack or sudden cardiac death)
  • Prevention or treatment of metabolic disease, type 2 diabetes, obesity
  • Prevention or treatment of autoimmune disease (multiple sclerosis, rheumatoid arthritis, thyroiditis, type 1 diabetes, psoriasis, auto-immune hepatitis)
  • Prevention or treatment of neuro-degenerative disease (dementia, Alzheimer, Parkinson, depression, autism, rare and devastating neurological disease)
  • Prevention or treatment of eating disorders (anorexia nervosa, binge eating, bulimia nervosa)
  • Prevention or treatment of inflammatory diseases (colitis, allergies, eczema, chronic lung disease)
  • Rehabilitation following cancer treatment, restauration of the immune system
  • Infertility, improvement of reproductive health, prevention of pregnancy complications
  • Early menopause, hormonal involution, loss of libido, painful sexual intercourse, erectile dysfunction
  • Lifespan extension, improvement in vitality, male performance, female wellbeing






  • A 46 years old successful entrepreneur from Russia’s pacific coast, with alcohol dependency and depression, his fiancée requested him to undergo treatment before marriage. Following six gut microbiome transfers from a completely alcohol- and drug-free merry donor, he has been clear of alcohol for one year, and was able to resume “social” drinking of one to two glasses of wine only for dinner during his 2nd “sober year”. His mood is stable, work and social performance is no longer endangered.  By now the wedding has taken place and the marriage is harmonious.
  • A 61 years old housewife and society lady from Kazan with diffuse hair loss that is unresponsive to medical therapy, undergoes three microbiome exchange treatments, she is pleased with fuller hair and smoother skin six months later, therefore, doesn’t avoid public events anymore, and resumes her roles in beneficence.
  • A gifted 18 years young Australian student with polycystic ovary syndrome, menstrual abnormality, weight gain, acne, virilisation and severe reactive depression with indigestion and obstipation, undergoes three gut microbiome exchange treatments and is started on a combination oral contraceptive. She loses 12kg within 12 months, her skin clears, and virilisation is reversed, bowel movements normalised, she has become again a popular and outgoing young lady.
  • A 43 years old Chinese entrepreneur with premature menopause undergoes three gut and vaginal microbiome exchange treatments, her menstrual cycle has resumed and is regular three months later. There are no more hot flushes. Sexual intercourse is no more painful.
  • A 62 years old politician from Indonesia presents for general rejuvenation treatment, two months after three microbiome exchange treatments, his friends notice a “miraculously” improved golf swing that is now “silky smooth”. His exercise tolerance and oxygen uptake improved, and the telomere length increased from 6178 pb, i.e. second lowest quartile, to 6408 pb, i.e. second highest quartile of the normal range, reflecting an increase in lifespan.
  • A 26 years old Stanford creative writing student with long standing and recurrent inflammatory disease of unknown cause with constitutional complaints, musculo-skeletal symptoms, long confinement to bed, recurrent diarrhea undergoes three microbiome exchange treatments, almost a year later she has resumed her studies without limitations and had almost forgotten that she ever had been handicapped before. 
  • A 29 years old business student from Indonesia, got involved in a robbery incident, and suffered cerebral trauma when pushed from his motorcycle, with two weeks in coma. Recovery after the hospital stay had not been complete, due to cognitive impairment, slowed speech, double vision, decreased performance, anxiety, depression and impaired self esteem with consequent increase in body weight and loss in former interests. Following six microbiome exchange treatments and six months later, he has resumed working out twice per week with his personal trainer, restored his social relations and former popularity. He feels confident enough now to apply for a job.
  • A 22 years old model from Columbia, suffering from recurrent abdominal pain, and constipation following abdominal surgery for malrotation in childhood, becomes completely asymptomatic two months following microbiome exchange treatments.







  • We offer novel treatment programs in regenerative medicine at The Dolder Grand Health & Aesthetic Link practice, in cooperation with Double Check Swiss Academic Center Zurich and leading Swiss medical institutions, both private and University-associated
  • Stand out among your peers, come for measurable and lasting health benefits, fresh looks and vitality
  • Look and feel younger than your age
  • Increase wellbeing, prowess and physical magnetism
  • For hormonal renewal and lifespan extension (telomere length ↑)
  • For improved overall health and metabolism (blood lipids↓ & sugar ↓)
  • For prevention or treatment of difficult-to-treat ailments, accelerated aging, auto-immune disease, inflammatory disease, degenerative diseases of the nervous system, depression, anorexia nervosa, bulimia nervosa, diabetes, obesity, and heart disease (coronary artery disease, heart failure)




  • This program provides support for the application of microbiome-based regenerative therapy  in a controlled and safe setting. All accompanying state-of-the-art diagnostic and therapeutic measures including checkup examinations are provided by the Double Check Center in Zurich (www.doublecheck.ch). Basis of this program is a general health program, duration one to seven days.
  • Day 0:  Check-in at your hotel or clinic, first consultation, program set-up
  • Day 1: Somatic checkup (at Double Check)
  • Double Check examination, depending on the patient’s preferences and needs (Executive / Executive plus, Individual)
  • Comprehensive laboratory testing, toxicology screening
  • Biological age (as measured by telomere length)
  • Further diagnostics, imaging, endoscopy if needed and desired
  • Day 1-3: Choices of regenerative medicine therapies
  • Day 2-7: Choices of personal training and enhancement
  • Day 1-7: Final assessment  with PD Dr. R. Arendt, hand-out of medical report with recommendations and prescriptions


Our donors are the most active, enthusiastic and blissful young people






  • A Double Check Executive Checkup  
    Alternative: Executive Plus Checkup 
  • Additional laboratory (hormones, xenobiotic metals, toxins)
  • Genetic assessment  of life span (telomere length)
  • Micro RNA extracts
  •    8 I.M. injections for repair   
  •    12 I.M. injections for repair
  • Gut microbiome exchange
        for 3 treatments
        for 5 treatments
  • Face rejuvenation by skin microbiome exchange
        for 3 treatments
  • Vaginal rejuvenation by vaginal microbiome exchange
       for 3 treatments
  • Oral chelation (detox) therapy per week
  • Consultation with PD Dr. Rainer Arendt
      o internal medicine, cardiology
      o personal coaching, autohypnosis, EMDR, HT (per hour) 
  • Consultation with co-therapists
      o Personal coaching / training (per hour)
      o Mogalates posture and embodiment therapy (per hour) 
  • Optional: Consultation with specialists in all medical fields
  • Holistic and biological addiction treatment (per week)
  • Holistic and biological treatment of eating disorders (per week)




“Youth — nothing else worth having in the world…and I had youth, the transitory, the fugitive, now, completely and abundantly. Yet what was I going to do with it?
I wanted freedom, freedom to indulge in whatever caprice struck my fancy, freedom to search in the farthermost corners of the earth for the beautiful, the joyous and the romantic.”

Richard Halliburton, 
The Royal Road to Romance (1925)














For your individually tailored health and regeneration package contact us